Pancreas
• Pancreas is an exo-endocrine gland.
• It has thin capsule, septa from capsule divides gland into lobules,
• Pancreatic acini are compactly arranged.
• Biphasic stain more pronounced, apical portion of cell cytoplasm is eosinophilie (zymogen granules) and basal portion is basophilic.
• Centroacinar cells are the beginning of the intercalated ducts which are seen at the center of the acini.
• Islets of Langerhans forms endocrine part of gland. Highly vascular
-it consists of polyhedral cells which are of three types-alpha, beta, delta.
Beta cells form 70% of islets, located in the center and secrete insulin.
Alpha cells make 20%, located peripherally and secrete glucagon.
Delta cells secrete stomatostatin